5ixb

X-ray diffraction
1.39Å resolution

Structure of human Melanoma Inhibitory Activity (MIA) Protein in complex with Pyrimidin-2-amine

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
PDBe Complex ID:
PDB-CPX-172553 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Melanoma-derived growth regulatory protein Chains: A, B
Molecule details ›
Chains: A, B
Length: 108 amino acids
Theoretical weight: 12.26 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q16674 (Residues: 25-131; Coverage: 100%)
Gene name: MIA
Sequence domains: Variant SH3 domain
Structure domains: SH3 Domains

Ligands and Environments

2 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SLS BEAMLINE X10SA
Spacegroup: P212121
Unit cell:
a: 47.44Å b: 47.48Å c: 87.49Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.134 0.132 0.16
Expression system: Escherichia coli