› 5iyp

X-ray diffraction
1.27Å resolution

Protruding domain of GII.4 human norovirus CHDC2094 in complex with HBGA type A (triglycan)

Released:
DOI: 10.2210/pdb5iyp/pdb
PDB entry 5iyp coloured by chain, front view.
PDB entry 5iyp coloured by chain, side view.
PDB entry 5iyp coloured by chain, top view.
Source organism: Norovirus Hu/GII.4/CHDC2094/1974/US
Entry authors: Singh BK, Hansman GS

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domain:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-112045 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecules (2 distinct):
VP1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 306 amino acids
Theoretical weight: 33.74 KDa
Source organism: Norovirus Hu/GII.4/CHDC2094/1974/US
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: D0QJ68 (Residues: 225-529; Coverage: 57%)
Sequence domains: Calicivirus coat protein C-terminal
Structure domains:

Ligands and Environments

Carbohydrate polymer : NEW Components: GLA, FUC, A2G
Carbohydrate polymer
2 bound ligands:
Ligand EDO 7 x EDO
Ligand FLC 1 x FLC
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID23-1
Spacegroup: I222
Unit cell:
a: 89.71Å b: 106.12Å c: 135.92Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.136 0.135 0.159
Expression system: Escherichia coli BL21(DE3)

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