› 5j6r

X-ray diffraction
4.01Å resolution

Crystal structure of Human Papillomavirus Type 59 L1 pentamer

Released:
DOI: 10.2210/pdb5j6r/pdb
PDB entry 5j6r coloured by chain, front view.
PDB entry 5j6r coloured by chain, side view.
PDB entry 5j6r coloured by chain, top view.
Source organism: human papillomavirus 59
Primary publication:
The C-Terminal Arm of the Human Papillomavirus Major Capsid Protein Is Immunogenic and Involved in Virus-Host Interaction.
Li Z, Yan X, Yu H, Wang D, Song S, Li Y, He M, Hong Q, Zheng Q, Zhao Q, Gu Y, Zhang J, Janssen ME, Cardone G, Olson NH, Baker TS, Li S, Xia N
Structure 24 874-85 (2016)
PMID: 27276427

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo pentamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-182452 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Major capsid protein L1 Chains: A, B, C, D, E, F, G, H, I, J
Molecule details ›
Chains: A, B, C, D, E, F, G, H, I, J
Length: 500 amino acids
Theoretical weight: 55.96 KDa
Source organism: human papillomavirus 59
Expression system: Escherichia coli
UniProt:
  • Canonical: Q81971 (Residues: 10-508; Coverage: 98%)
Gene names: L1, ORF putative L1
Sequence domains: L1 (late) protein

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRF BEAMLINE BL17U
Spacegroup: P21
Unit cell:
a: 114.242Å b: 161.743Å c: 154.729Å
α: 90° β: 110.34° γ: 90°
R-values:
R R work R free
0.244 0.243 0.267
Expression system: Escherichia coli

Quick links

Citations

3 review citations

Human papillomavirus first and second generation vaccines-current status and future directions.
Pouyanfard et al. (2017)
2 more

4 mentions without citation

The C-Terminal Arm of the Human Papillomavirus Major Capsid Protein Is Immunogenic and Involved in Virus-Host Interaction.
Li et al. (2016)
3 more