5jp2

X-ray diffraction
2.4Å resolution

Fcho1 Mu homology domain (Danio Rerio) with bound Eps15 peptide

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
PDBe Complex ID:
PDB-CPX-102641 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Epidermal growth factor receptor substrate 15 Chains: E, F
Molecule details ›
Chains: E, F
Length: 27 amino acids
Theoretical weight: 2.85 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P42566 (Residues: 615-637; Coverage: 3%)
Gene names: AF1P, EPS15
F-BAR domain only protein 1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 286 amino acids
Theoretical weight: 31.23 KDa
Source organism: Danio rerio
Expression system: Escherichia coli
UniProt:
  • Canonical: A0A0R4IA99 (Residues: 859-1144; Coverage: 25%)
Gene name: fcho1
Sequence domains: Muniscin C-terminal mu homology domain

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I04-1
Spacegroup: R3
Unit cell:
a: 239.778Å b: 239.778Å c: 44.091Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.201 0.199 0.234
Expression system: Escherichia coli