Function and Biology Details
Reaction catalysed:
Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
- WD40 repeat
- G-protein beta WD-40 repeat
- WD40/YVTN repeat-like-containing domain superfamily
- WD40-repeat-containing domain superfamily
- Ubiquitin specific protease, conserved site
- WD40 repeat, conserved site
- Ubiquitin specific protease domain
- Peptidase C19, ubiquitin carboxyl-terminal hydrolase
1 more domain
Structure analysis Details
Assembly composition:
hetero trimer (preferred)
PDBe Complex ID:
PDB-CPX-130891 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):