› 5k1g

X-ray diffraction
1.9Å resolution

Crystal structure of reduced Prx3 from Vibrio vulnificus

Released:
DOI: 10.2210/pdb5k1g/pdb
Model geometry
Fit model/data
PDB entry 5k1g coloured by chain, front view.
PDB entry 5k1g coloured by chain, side view.
PDB entry 5k1g coloured by chain, top view.
Source organism: Vibrio vulnificus MO6-24/O
Primary publication:
Crystal structure of peroxiredoxin 3 from Vibrio vulnificus and its implications for scavenging peroxides and nitric oxide.
Ahn J, Jang KK, Jo I, Nurhasni H, Lim JG, Yoo JW, Choi SH, Ha NC
OpenAccess logo IUCrJ 5 82-92 (2018)
PMID: 29354274

Function and Biology Details

Reaction catalysed: 
2 glutathione + ROOH = glutathione disulfide + H(2)O + ROH
Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-103905 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Glutathione-dependent peroxiredoxin Chain: A
Molecule details ›
Chain: A
Length: 164 amino acids
Theoretical weight: 17.55 KDa
Source organism: Vibrio vulnificus MO6-24/O
Expression system: Escherichia coli
UniProt:
  • Canonical: A0A1Z0YU25 (Residues: 1-164; Coverage: 100%)
Sequence domains: Redoxin
Structure domains: Glutaredoxin

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this entry.
X-ray source: PAL/PLS BEAMLINE 5C (4A)
Spacegroup: P3221
Unit cell:
a: 73.871Å b: 73.871Å c: 62.254Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.224 0.22 0.258
Expression system: Escherichia coli

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Citations

2 citation in other articles

Transcriptomic Identification and Biochemical Characterization of HmpA, a Nitric Oxide Dioxygenase, Essential for Pathogenesis of Vibrio vulnificus.
Kim et al. (2019)
1 more

2 mentions without citation

Peroxiredoxins wear many hats: Factors that fashion their peroxide sensing personalities.
Bolduc et al. (2021)
1 more