› 5k4c

X-ray diffraction
1.7Å resolution

Structure of eukaryotic translation initiation factor 3 subunit D (eIF3d) cap binding domain from Nasonia vitripennis, Crystal form 2

Released:
DOI: 10.2210/pdb5k4c/pdb
Model geometry
Fit model/data
PDB entry 5k4c coloured by chain, front view.
PDB entry 5k4c coloured by chain, side view.
PDB entry 5k4c coloured by chain, top view.
Source organism: Nasonia vitripennis
Primary publication:
eIF3d is an mRNA cap-binding protein that is required for specialized translation initiation.
Lee AS, Kranzusch PJ, Doudna JA, Cate JH
OpenAccess logo Nature 536 96-9 (2016)
PMID: 27462815

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
Sequence domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-125581 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Eukaryotic translation initiation factor 3 subunit D Chain: A
Molecule details ›
Chain: A
Length: 368 amino acids
Theoretical weight: 42.2 KDa
Source organism: Nasonia vitripennis
Expression system: Escherichia coli
UniProt:
  • Canonical: K7IM66 (Residues: 172-537; Coverage: 66%)
Sequence domains: Eukaryotic translation initiation factor 3 subunit 7 (eIF-3)

Ligands and Environments

1 bound ligand:
Ligand GOL 3 x GOL
No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this entry.
X-ray source: ALS BEAMLINE 8.3.1
Spacegroup: P212121
Unit cell:
a: 49.011Å b: 61.844Å c: 138.311Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.163 0.162 0.196
Expression system: Escherichia coli

Quick links

Citations

68 review citations

Functions of N6-methyladenosine and its role in cancer.
He et al. (2019)
67 more

1 mention without citation

eIF3d is an mRNA cap-binding protein that is required for specialized translation initiation.
Lee et al. (2016)