› 5k8a

X-ray diffraction
2Å resolution

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-230504 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
humanized Fab Lite chain Chains: A, E, L, M
Molecule details ›
Chains: A, E, L, M
Length: 213 amino acids
Theoretical weight: 23.15 KDa
Source organism: Mus musculus
Expression system: Homo sapiens
Structure domains: Immunoglobulins
Heavy chain Chains: B, F, H, V
Molecule details ›
Chains: B, F, H, V
Length: 227 amino acids
Theoretical weight: 24.53 KDa
Source organism: Mus musculus
Expression system: Homo sapiens
Structure domains: Immunoglobulins

Ligands and Environments

No bound ligands
1 modified residue:
Ligand PCA 4 x PCA

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 19-ID
Spacegroup: I222
Unit cell:
a: 149.156Å b: 149.203Å c: 195.032Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.166 0.164 0.189
Expression system: Homo sapiens

Quick links

Citations

3 citation in other articles

Assessment of the Higher-Order Structure of Formulated Monoclonal Antibody Therapeutics by 2D Methyl Correlated NMR and Principal Component Analysis.
Arbogast et al. (2020)
2 more

15 mentions without citation

Fourier-transform ion cyclotron resonance mass spectrometry for characterizing proteoforms.
Tucholski et al. (2022)
14 more