› 5kba

X-ray diffraction
2.6Å resolution

Computational Design of Self-Assembling Cyclic Protein Homooligomers

Released:
DOI: 10.2210/pdb5kba/pdb
Model geometry
Fit model/data
PDB entry 5kba coloured by chain, front view.
PDB entry 5kba coloured by chain, side view.
PDB entry 5kba coloured by chain, top view.
Source organism: synthetic construct
Primary publication:
Computational design of self-assembling cyclic protein homo-oligomers.
Fallas JA, Ueda G, Sheffler W, Nguyen V, McNamara DE, Sankaran B, Pereira JH, Parmeggiani F, Brunette TJ, Cascio D, Yeates TR, Zwart P, Baker D
OpenAccess logo Nat Chem 9 353-360 (2017)
PMID: 28338692

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-165889 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Designed protein ANK1C2 Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 169 amino acids
Theoretical weight: 18.13 KDa
Source organism: synthetic construct
Expression system: Escherichia coli
Structure domains: Ankyrin repeat-containing domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this entry.
X-ray source: ALS BEAMLINE 8.2.2
Spacegroup: C2
Unit cell:
a: 93.372Å b: 48.817Å c: 139.267Å
α: 90° β: 98.87° γ: 90°
R-values:
R R work R free
0.203 0.201 0.239
Expression system: Escherichia coli

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Citations

10 review citations

Evolving SAXS versatility: solution X-ray scattering for macromolecular architecture, functional landscapes, and integrative structural biology.
Brosey et al. (2019)
9 more

3 mentions without citation

Computational design of self-assembling cyclic protein homo-oligomers.
Fallas et al. (2017)
2 more