› 5kbt

Electron Microscopy
6.4Å resolution

Cryo-EM structure of GluA2-1xSTZ complex at 6.4 Angstrom resolution

Released:
DOI: 10.2210/pdb5kbt/pdb
PDB entry 5kbt coloured by chain, front view.
PDB entry 5kbt coloured by chain, side view.
PDB entry 5kbt coloured by chain, top view.
Source organisms:
Primary publication:
Elucidation of AMPA receptor-stargazin complexes by cryo-electron microscopy.
Twomey EC, Yelshanskaya MV, Grassucci RA, Frank J, Sobolevsky AI
Science 353 83-6 (2016)
PMID: 27365450
Related structures: EMD-8230

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-131564 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Glutamate receptor 2; Voltage-dependent calcium channel gamma-2 subunit Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 1034 amino acids
Theoretical weight: 115.52 KDa
Source organisms: Expression system: Homo sapiens
UniProt:
  • Canonical: P19491 (Residues: 25-847; Coverage: 95%)
  • Canonical: O88602 (Residues: 2-208; Coverage: 64%)
Gene names: Cacng2, GluA2, Glur2, Gria2, Stg
Sequence domains:

Ligands and Environments

2 bound ligands:
Ligand ZK1 4 x ZK1
Ligand NAG 4 x NAG
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 6.4Å
Relevant EMDB volumes: EMD-8230
Expression system: Homo sapiens

Quick links

Citations

23 review citations

Structural and Functional Architecture of AMPA-Type Glutamate Receptors and Their Auxiliary Proteins.
Greger et al. (2017)
22 more

2 mentions without citation

Elucidation of AMPA receptor-stargazin complexes by cryo-electron microscopy.
Twomey et al. (2016)
1 more