› 5kc5

X-ray diffraction
2.35Å resolution

Crystal structure of the Cbln1 C1q domain trimer

Released:
DOI: 10.2210/pdb5kc5/pdb
PDB entry 5kc5 coloured by chain, front view.
PDB entry 5kc5 coloured by chain, side view.
PDB entry 5kc5 coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Structural basis for integration of GluD receptors within synaptic organizer complexes.
Elegheert J, Kakegawa W, Clay JE, Shanks NF, Behiels E, Matsuda K, Kohda K, Miura E, Rossmann M, Mitakidis N, Motohashi J, Chang VT, Siebold C, Greger IH, Nakagawa T, Yuzaki M, Aricescu AR
Science 353 295-9 (2016)
PMID: 27418511

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo trimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-149958 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Cerebellin-1 Chain: A
Molecule details ›
Chain: A
Length: 147 amino acids
Theoretical weight: 16.64 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
  • Canonical: P23435 (Residues: 58-193; Coverage: 79%)
Gene name: CBLN1
Sequence domains: C1q domain
Structure domains: Jelly Rolls

Ligands and Environments

1 bound ligand:
Ligand NAG 1 x NAG
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I04
Spacegroup: P6
Unit cell:
a: 83.42Å b: 83.42Å c: 50.57Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.181 0.177 0.197
Expression system: Homo sapiens

Quick links

Citations

28 review citations

Synaptic Neurexin Complexes: A Molecular Code for the Logic of Neural Circuits.
Südhof TC. (2017)
27 more

2 mentions without citation

Neurexins - versatile molecular platforms in the synaptic cleft.
Rudenko G. (2019)
1 more