› 5kc7

X-ray diffraction
7.04Å resolution

Crystal structure of Cbln1 (Val55-Gly58 deletion mutant)

Released:
DOI: 10.2210/pdb5kc7/pdb
PDB entry 5kc7 coloured by chain, front view.
PDB entry 5kc7 coloured by chain, side view.
PDB entry 5kc7 coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Structural basis for integration of GluD receptors within synaptic organizer complexes.
Elegheert J, Kakegawa W, Clay JE, Shanks NF, Behiels E, Matsuda K, Kohda K, Miura E, Rossmann M, Mitakidis N, Motohashi J, Chang VT, Siebold C, Greger IH, Nakagawa T, Yuzaki M, Aricescu AR
Science 353 295-9 (2016)
PMID: 27418511

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo hexamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-216321 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Cerebellin-1 Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 178 amino acids
Theoretical weight: 19.77 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
  • Canonical: P23435 (Residues: 24-193; Coverage: 97%)
Gene name: CBLN1
Sequence domains: C1q domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I03
Spacegroup: I213
Unit cell:
a: 187.45Å b: 187.45Å c: 187.45Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.277 0.27 0.351
Expression system: Homo sapiens

Quick links

Citations

28 review citations

Synaptic Neurexin Complexes: A Molecular Code for the Logic of Neural Circuits.
Südhof TC. (2017)
27 more

2 mentions without citation

Neurexins - versatile molecular platforms in the synaptic cleft.
Rudenko G. (2019)
1 more