› 5kcb

X-ray diffraction
2.1Å resolution

The structure of SAV2435 bound to ethidium bromide

Released:
DOI: 10.2210/pdb5kcb/pdb
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PDB entry 5kcb coloured by chain, front view.
PDB entry 5kcb coloured by chain, side view.
PDB entry 5kcb coloured by chain, top view.
Source organism: Staphylococcus aureus subsp. aureus N315
Primary publication:
Solution Binding and Structural Analyses Reveal Potential Multidrug Resistance Functions for SAV2435 and CTR107 and Other GyrI-like Proteins.
Moreno A, Froehlig JR, Bachas S, Gunio D, Alexander T, Vanya A, Wade H
Biochemistry 55 4850-63 (2016)
PMID: 27505298

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-295116 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
SA2223 protein Chain: A
Molecule details ›
Chain: A
Length: 165 amino acids
Theoretical weight: 18.75 KDa
Source organism: Staphylococcus aureus subsp. aureus N315
Expression system: Escherichia coli
UniProt:
  • Canonical: A0A0H3JRN6 (Residues: 1-157; Coverage: 100%)
Sequence domains: Integron-associated effector binding protein
Structure domains: Regulatory factor, effector binding domain

Ligands and Environments

2 bound ligands:
Ligand ET 1 x ET
Ligand SO4 3 x SO4
No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this entry.
X-ray source: RIGAKU FR-E SUPERBRIGHT
Spacegroup: P41212
Unit cell:
a: 73.72Å b: 73.72Å c: 68.53Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.2 0.199 0.219
Expression system: Escherichia coli

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Citations

1 review citation

Bacterial MerR family transcription regulators: activationby distortion.
Fang et al. (2022)
7 other articles

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