5kg9

X-ray diffraction
2.3Å resolution

Crystal structure of the gp120 v2 antibody RE505-22 Fab from IGH- and IGK-humanized mouse

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
PDBe Complex ID:
PDB-CPX-230506 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Antibody RE505-22 Fab heavy chain Chains: A, H
Molecule details ›
Chains: A, H
Length: 221 amino acids
Theoretical weight: 23.68 KDa
Source organism: Mus musculus
Expression system: Homo sapiens
Structure domains: Immunoglobulins
Antibody RE505-22 Fab light chain Chains: B, L
Molecule details ›
Chains: B, L
Length: 221 amino acids
Theoretical weight: 23.77 KDa
Source organism: Mus musculus
Expression system: Homo sapiens
Structure domains: Immunoglobulins

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 22-ID
Spacegroup: P212121
Unit cell:
a: 72.183Å b: 76.749Å c: 184.287Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.242 0.24 0.281
Expression system: Homo sapiens