› 5kgz

Solution NMR

Phenol-soluble modulin Beta2

Released:
DOI: 10.2210/pdb5kgz/pdb
PDB entry 5kgz coloured by chain, ensemble of 20 models, front view.
PDB entry 5kgz coloured by chain, ensemble of 20 models, side view.
PDB entry 5kgz coloured by chain, ensemble of 20 models, top view.
Source organism: Staphylococcus aureus
Primary publication:
Solution Structures of Phenol-Soluble Modulins α1, α3, and β2, Virulence Factors from Staphylococcus aureus.
Towle KM, Lohans CT, Miskolzie M, Acedo JZ, van Belkum MJ, Vederas JC
Biochemistry 55 4798-806 (2016)
PMID: 27525453

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-124911 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Antibacterial protein 3 Chain: A
Molecule details ›
Chain: A
Length: 44 amino acids
Theoretical weight: 4.46 KDa
Source organism: Staphylococcus aureus
Expression system: Escherichia coli
UniProt:
  • Canonical: H9BRQ4 (Residues: 1-44; Coverage: 100%)
Gene names: A6760_05220, BN1321_240017, E1948_05155, E1948_05715, EP54_05735, EQ90_05585, FAF17_11495, G6W63_02835, G6Y24_13430, GO793_12150, GO814_06585, GO941_11740, GO942_07025, GQX37_07230, GZ156_11565, GZ163_08815, H2639_05155, HMPREF3211_00853, M1K003_0014, NCTC10702_01854, NCTC13131_00468, NCTC5664_02402, NCTC7972_00778, QU38_12205, SAMEA1531744_01474, SAMEA2078260_01574, SAMEA2078588_01560, SAMEA2080344_01743, SAMEA2081063_01422, SAMEA4008575_01912, SAMEA70146418_01738, SAMEA70153168_01735, SAMEA70245418_02022, psm beta2
Sequence domains: Phenol-soluble modulin beta protein

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 49%
Expression system: Escherichia coli

Quick links

Citations

4 review citations

Staphylococcus aureus Secreted Toxins and Extracellular Enzymes.
Tam et al. (2019)
3 more

3 mentions without citation

Staphylococcus aureus Phenol-Soluble Modulins α1-α3 Act as Novel Toll-Like Receptor (TLR) 4 Antagonists to Inhibit HMGB1/TLR4/NF-κB Signaling Pathway.
Chu et al. (2018)
2 more