› 5klq

X-ray diffraction
3.4Å resolution

Crystal structure of HopZ1a in complex with IP6 and CoA

Released:
DOI: 10.2210/pdb5klq/pdb
PDB entry 5klq coloured by chain, front view.
PDB entry 5klq coloured by chain, side view.
PDB entry 5klq coloured by chain, top view.
Source organism: Pseudomonas syringae pv. syringae
Primary publication:
Structure of a pathogen effector reveals the enzymatic mechanism of a novel acetyltransferase family.
Zhang ZM, Ma KW, Yuan S, Luo Y, Jiang S, Hawara E, Pan S, Ma W, Song J
Nat Struct Mol Biol 23 847-52 (2016)
PMID: 27525589

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-180457 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Serine/threonine-protein acetyltransferase HopZ1a Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 342 amino acids
Theoretical weight: 37.98 KDa
Source organism: Pseudomonas syringae pv. syringae
Expression system: Enterobacteria phage L1
UniProt:
  • Canonical: Q6VE93 (Residues: 29-369; Coverage: 92%)
Gene names: ALP25_03258, hopZ1a
Sequence domains: YopJ Serine/Threonine acetyltransferase

Ligands and Environments

3 bound ligands:
Ligand IHP 3 x IHP
Ligand COA 3 x COA
Ligand CIT 1 x CIT
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 5.0.1
Spacegroup: P1
Unit cell:
a: 49.131Å b: 82.295Å c: 86.268Å
α: 64.2° β: 76.69° γ: 89.35°
R-values:
R R work R free
0.239 0.234 0.282
Expression system: Enterobacteria phage L1

Quick links

Citations

11 review citations

Oh, the places they'll go! A survey of phytopathogen effectors and their host targets.
Khan et al. (2018)
10 more

2 mentions without citation

YopJ Family Effectors Promote Bacterial Infection through a Unique Acetyltransferase Activity.
Ma et al. (2016)
1 more