› 5kww

X-ray diffraction
2.5Å resolution

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo trimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-125887 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Fibritin C-terminal domain-containing protein; Fusion glycoprotein F0 Chain: F
Molecule details ›
Chain: F
Length: 568 amino acids
Theoretical weight: 63.22 KDa
Source organisms: Expression system: Homo sapiens
UniProt:
  • Canonical: P03420 (Residues: 1-513; Coverage: 89%)
  • Canonical: M1E1E4 (Residues: 1-28; Coverage: 48%)
Gene name: F
Sequence domains:

Ligands and Environments

4 bound ligands:
Ligand NAG 1 x NAG
Ligand NHE 1 x NHE
Ligand SO4 10 x SO4
Ligand 6YA 1 x 6YA
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 5.0.2
Spacegroup: P4132
Unit cell:
a: 169.99Å b: 169.99Å c: 169.99Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.212 0.21 0.239
Expression system: Homo sapiens

Quick links

Citations

16 review citations

Innovation and trends in the development and approval of antiviral medicines: 1987-2017 and beyond.
Chaudhuri et al. (2018)
15 more

6 mentions without citation

Structural Insight into Paramyxovirus and Pneumovirus Entry Inhibition.
Aggarwal et al. (2020)
5 more