Function and Biology Details
Reactions catalysed:
GDP-beta-L-fucose + [protein]-(L-serine/L-threonine) = GDP + [protein]-3-O-(alpha-L-fucosyl)-(L-serine/L-threonine)
Selective cleavage of Arg-|-Ile bond in factor X to form factor Xa.
Biochemical function:
Biological process:
Cellular component:
Structure analysis Details
Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-159728 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
GDP-fucose protein O-fucosyltransferase 1
Molecule details ›
Chain: A
Length: 355 amino acids
Theoretical weight: 40.46 KDa
Source organism: Mus musculus
Expression system: Homo sapiens
UniProt:
Sequence domains: GDP-fucose protein O-fucosyltransferase
Structure domains:
Length: 355 amino acids
Theoretical weight: 40.46 KDa
Source organism: Mus musculus
Expression system: Homo sapiens
UniProt:
- Canonical:
Q91ZW2 (Residues: 33-384; Coverage: 97%)
Sequence domains: GDP-fucose protein O-fucosyltransferase
Structure domains:
Factor VII light chain
Molecule details ›
Chain: B
Length: 40 amino acids
Theoretical weight: 4.42 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
Sequence domains: EGF-like domain
Structure domains: Laminin
Length: 40 amino acids
Theoretical weight: 4.42 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
- Canonical: P70375 (Residues: 87-126; Coverage: 10%)
Sequence domains: EGF-like domain
Structure domains: Laminin
