› 5l09

X-ray diffraction
2Å resolution

Crystal Structure of Quorum-Sensing Transcriptional Activator from Yersinia enterocolitica in complex with 3-oxo-N-[(3S)-2-oxotetrahydrofuran-3-yl]hexanamide

Released:
DOI: 10.2210/pdb5l09/pdb
PDB entry 5l09 coloured by chain, front view.
PDB entry 5l09 coloured by chain, side view.
PDB entry 5l09 coloured by chain, top view.
Source organism: Yersinia enterocolitica subsp. enterocolitica 8081
Entry authors: Kim Y, Chhor G, Jedrzejczak R, Winans SC, Anderson WF, Joachimiak A, Center for Structural Genomics of Infectious Diseases (CSGID)

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-106627 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
HTH luxR-type domain-containing protein Chains: A, B
Molecule details ›
Chains: A, B
Length: 179 amino acids
Theoretical weight: 21.15 KDa
Source organism: Yersinia enterocolitica subsp. enterocolitica 8081
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: A1JMX7 (Residues: 1-179; Coverage: 73%)
Gene names: YE1599, yenR
Sequence domains: Autoinducer binding domain
Structure domains: Transcription factor LuxR-like, autoinducer-binding domain

Ligands and Environments

4 bound ligands:
Ligand 482 2 x 482
Ligand SO4 3 x SO4
Ligand EDO 8 x EDO
Ligand ACY 4 x ACY
1 modified residue:
Ligand MSE 10 x MSE

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 19-ID
Spacegroup: C2221
Unit cell:
a: 63.878Å b: 122.775Å c: 107.603Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.171 0.169 0.203
Expression system: Escherichia coli BL21(DE3)

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