Function and Biology Details
Reaction catalysed:
GTP + H(2)O = GDP + phosphate
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
- Signal recognition particle, SRP54 subunit, GTPase domain
- P-loop containing nucleoside triphosphate hydrolase
- Signal recognition particle SRP54, helical bundle
- Signal recognition particle, SRP54 subunit, M-domain superfamily
- AAA+ ATPase domain
- Signal recognition particle SRP54, N-terminal domain superfamily
- Signal recognition particle, SRP54 subunit
- SRP/SRP receptor, N-terminal
4 more domains
Structure analysis Details
Assembly composition:
hetero dimer (preferred)
Assembly name:
Signal recognition particle (preferred)
PDBe Complex ID:
PDB-CPX-140057 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Signal recognition particle subunit SRP54
Molecule details ›
Chains: A, C
Length: 442 amino acids
Theoretical weight: 49.13 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Sequence domains:
Length: 442 amino acids
Theoretical weight: 49.13 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical:
P61011 (Residues: 1-436; Coverage: 87%)
Sequence domains:
- SRP54-type protein, helical bundle domain
- SRP54-type protein, GTPase domain
- Signal peptide binding domain
Signal recognition particle receptor subunit alpha
Molecule details ›
Chains: B, D
Length: 638 amino acids
Theoretical weight: 69.91 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Sequence domains:
Length: 638 amino acids
Theoretical weight: 69.91 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical: P08240 (Residues: 1-638; Coverage: 100%)
Sequence domains:
- SRP54-type protein, helical bundle domain
- SRP54-type protein, GTPase domain
- Signal recognition particle, alpha subunit, N-terminal
