› 5l3w

X-ray diffraction
2.4Å resolution

Structure of the crenarchaeal FtsY GTPase bound to GDP

Released:
DOI: 10.2210/pdb5l3w/pdb
PDB entry 5l3w coloured by chain, front view.
PDB entry 5l3w coloured by chain, side view.
PDB entry 5l3w coloured by chain, top view.
Source organism: Sulfolobus acidocaldarius
Primary publication:
Structural Basis for Conserved Regulation and Adaptation of the Signal Recognition Particle Targeting Complex.
Wild K, Bange G, Motiejunas D, Kribelbauer J, Hendricks A, Segnitz B, Wade RC, Sinning I
J Mol Biol 428 2880-97 (2016)
PMID: 27241309

Function and Biology Details

Reaction catalysed: 
GTP + H(2)O = GDP + phosphate
Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-150997 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Signal recognition particle receptor FtsY Chain: A
Molecule details ›
Chain: A
Length: 306 amino acids
Theoretical weight: 34.63 KDa
Source organism: Sulfolobus acidocaldarius
Expression system: Escherichia coli
UniProt:
  • Canonical: P27414 (Residues: 69-368; Coverage: 81%)
Gene names: Saci_1462, dpa, ftsY, sso
Sequence domains:

Ligands and Environments

2 bound ligands:
Ligand GDP 1 x GDP
Ligand SO4 1 x SO4
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID14-1
Spacegroup: R3
Unit cell:
a: 144.906Å b: 144.906Å c: 49.723Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.176 0.171 0.218
Expression system: Escherichia coli

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Citations

5 review citations

Electrostatic Interactions in Protein Structure, Folding, Binding, and Condensation.
Zhou et al. (2018)
4 more