› 5l93

Electron Microscopy
3.9Å resolution

An atomic model of HIV-1 CA-SP1 reveals structures regulating assembly and maturation

Released:
DOI: 10.2210/pdb5l93/pdb
PDB entry 5l93 coloured by chain, front view.
PDB entry 5l93 coloured by chain, side view.
PDB entry 5l93 coloured by chain, top view.
Source organism: Human immunodeficiency virus type 1 (NEW YORK-5 ISOLATE)
Primary publication:
An atomic model of HIV-1 capsid-SP1 reveals structures regulating assembly and maturation.
Schur FK, Obr M, Hagen WJ, Wan W, Jakobi AJ, Kirkpatrick JM, Sachse C, Kräusslich HG, Briggs JA
Science 353 506-8 (2016)
PMID: 27417497
Related structures: EMD-4015

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo octadecamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-146181 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Capsid protein p24 Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 224 amino acids
Theoretical weight: 24.79 KDa
Source organism: Human immunodeficiency virus type 1 (NEW YORK-5 ISOLATE)
Expression system: Escherichia coli
UniProt:
  • Canonical: P12493 (Residues: 148-371; Coverage: 45%)
Gene name: gag
Sequence domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 3.9Å
Relevant EMDB volumes: EMD-4015
Expression system: Escherichia coli

Quick links

Citations

64 review citations

Maturation of retroviruses.
Pornillos et al. (2019)
63 more

28 mentions without citation

Advances in coarse-grained modeling of macromolecular complexes.
Pak et al. (2018)
27 more