Function and Biology Details
Reactions catalysed:
S-adenosyl-L-methionine + a 5'-(5'-triphosphoguanosine)-[mRNA] = S-adenosyl-L-homocysteine + a 5'-(N(7)-methyl 5'-triphosphoguanosine)-[mRNA]
S-adenosyl-L-methionine + a 5'-(N(7)-methyl 5'-triphosphoguanosine)-(ribonucleotide)-[mRNA] = S-adenosyl-L-homocysteine + a 5'-(N(7)-methyl 5'-triphosphoguanosine)-(2'-O-methyl-ribonucleotide)-[mRNA]
Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1)
Selective hydrolysis of -Xaa-Xaa-|-Yaa- bonds in which each of the Xaa can be either Arg or Lys and Yaa can be either Ser or Ala.
NTP + H(2)O = NDP + phosphate
ATP + H(2)O = ADP + phosphate
Biochemical function:
Biological process:
- not assigned
Cellular component:
- not assigned
Sequence domains:
Structure analysis Details
Assembly composition:
hetero tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-207189 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (4 distinct):
Envelope protein E
Molecule details ›
Chains: A, B
Length: 447 amino acids
Theoretical weight: 48.49 KDa
Source organism: Zika virus
Expression system: Drosophila melanogaster
UniProt:
Length: 447 amino acids
Theoretical weight: 48.49 KDa
Source organism: Zika virus
Expression system: Drosophila melanogaster
UniProt:
- Canonical:
A0A024B7W1 (Residues: 291-698; Coverage: 12%)
- Flavivirus glycoprotein, central and dimerisation domains
- Flavivirus glycoprotein, immunoglobulin-like domain
Ligands and Environments
No modified residues
Experiments and Validation Details
X-ray source:
SOLEIL BEAMLINE PROXIMA 2
Spacegroup:
C2221
Expression system: Drosophila melanogaster
