› 5lf2

X-ray diffraction
1.85Å resolution

Crystal structure of laminin beta2 LE5-LF-LE6

Released:
DOI: 10.2210/pdb5lf2/pdb
PDB entry 5lf2 coloured by chain, front view.
PDB entry 5lf2 coloured by chain, side view.
PDB entry 5lf2 coloured by chain, top view.
Source organism: Rattus norvegicus
Primary publication:
Crystallographic analysis of the laminin β2 short arm reveals how the LF domain is inserted into a regular array of LE domains.
Pulido D, Briggs DC, Hua J, Hohenester E
Matrix Biol 57-58 204-212 (2017)
PMID: 27425256

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-147487 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Laminin subunit beta-2 Chains: A, B
Molecule details ›
Chains: A, B
Length: 315 amino acids
Theoretical weight: 34.52 KDa
Source organism: Rattus norvegicus
Expression system: Homo sapiens
UniProt:
  • Canonical: P15800 (Residues: 523-833; Coverage: 18%)
Gene name: Lamb2
Sequence domains:
Structure domains: Laminin

Ligands and Environments

2 bound ligands:
Ligand CA 2 x CA
Ligand CL 2 x CL
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I04-1
Spacegroup: C2
Unit cell:
a: 144.32Å b: 55.35Å c: 111.34Å
α: 90° β: 119.38° γ: 90°
R-values:
R R work R free
0.179 0.178 0.21
Expression system: Homo sapiens

Quick links

Citations

2 citation in other articles

Structural and functional analysis of two small leucine-rich repeat proteoglycans, fibromodulin and chondroadherin.
Paracuellos et al. (2017)
1 more

4 mentions without citation

Structural biology of laminins.
Hohenester E. (2019)
3 more