› 5lfn

X-ray diffraction
2.1Å resolution

Crystal structure of human chondroadherin

Released:
DOI: 10.2210/pdb5lfn/pdb
PDB entry 5lfn coloured by chain, front view.
PDB entry 5lfn coloured by chain, side view.
PDB entry 5lfn coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Crystal structure of human chondroadherin: solving a difficult molecular-replacement problem using de novo models.
Rämisch S, Pramhed A, Tillgren V, Aspberg A, Logan DT
Acta Crystallogr D Struct Biol 73 53-63 (2017)
PMID: 28045385

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-127431 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Chondroadherin Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 337 amino acids
Theoretical weight: 38.32 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
  • Canonical: O15335 (Residues: 23-359; Coverage: 100%)
Gene names: CHAD, SLRR4A
Sequence domains:
Structure domains: Ribonuclease Inhibitor

Ligands and Environments

1 bound ligand:
Ligand CL 2 x CL
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: MAX II BEAMLINE I911-3
Spacegroup: P21
Unit cell:
a: 56.48Å b: 111.59Å c: 128.68Å
α: 90° β: 92.22° γ: 90°
R-values:
R R work R free
0.246 0.245 0.262
Expression system: Homo sapiens

Quick links

Citations

5 citation in other articles

Crystallographic molecular replacement using an in silico-generated search model of SARS-CoV-2 ORF8.
Flower et al. (2021)
4 more

3 mentions without citation

Sequence features, structure, ligand interaction, and diseases in small leucine rich repeat proteoglycans.
Matsushima et al. (2021)
2 more