› 5lox

X-ray diffraction
2.9Å resolution

Helical Assembly of the Anbu Complex from Pseudomonas aeruginosa

Released:
DOI: 10.2210/pdb5lox/pdb
PDB entry 5lox coloured by chain, front view.
PDB entry 5lox coloured by chain, side view.
PDB entry 5lox coloured by chain, top view.
Source organism: Pseudomonas aeruginosa
Primary publication:
The Architecture of the Anbu Complex Reflects an Evolutionary Intermediate at the Origin of the Proteasome System.
Fuchs ACD, Alva V, Maldoner L, Albrecht R, Hartmann MD, Martin J
Structure 25 834-845.e5 (2017)
PMID: 28479063

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo 34-mer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-165960 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Peptidase Chains: 1, 2, 3, 4, 5, 6, 7, 8, A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P, Q, R, S, T, U, V, W, X, Y, Z
Molecule details ›
Chains: 1, 2, 3, 4, 5, 6, 7, 8, A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P, Q, R, S, T, U, V, W, X, Y, Z
Length: 242 amino acids
Theoretical weight: 26.65 KDa
Source organism: Pseudomonas aeruginosa
Expression system: Escherichia coli

Ligands and Environments

No bound ligands
1 modified residue:
Ligand MSE 170 x MSE

Experiments and Validation Details

Entry percentile scores
X-ray source: SLS BEAMLINE X10SA
Spacegroup: P21
Unit cell:
a: 150.07Å b: 230.08Å c: 171.72Å
α: 90° β: 108.39° γ: 90°
R-values:
R R work R free
0.199 0.198 0.218
Expression system: Escherichia coli

Quick links

Citations

5 citation in other articles

A High-Content Screening Assay for the Discovery of Novel Proteasome Inhibitors from Formosan Soft Corals.
Ling et al. (2018)
4 more

9 mentions without citation

Translational research involving oxidative stress and diseases of aging.
Floyd et al. (2011)
8 more