› 5lpi

X-ray diffraction
1.8Å resolution

Structure of the zinc finger array of Cep104

Released:
DOI: 10.2210/pdb5lpi/pdb
PDB entry 5lpi coloured by chain, front view.
PDB entry 5lpi coloured by chain, side view.
PDB entry 5lpi coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
The Ciliopathy-Associated Cep104 Protein Interacts with Tubulin and Nek1 Kinase.
Al-Jassar C, Andreeva A, Barnabas DD, McLaughlin SH, Johnson CM, Yu M, van Breugel M
Structure 25 146-156 (2017)
PMID: 28017521

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-129937 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Centrosomal protein of 104 kDa Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 134 amino acids
Theoretical weight: 15.55 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: O60308 (Residues: 746-875; Coverage: 14%)
Gene names: CEP104, KIAA0562
Sequence domains: Centrosomal protein CEP104, ZnF

Ligands and Environments

1 bound ligand:
Ligand ZN 16 x ZN
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU FR-E SUPERBRIGHT
Spacegroup: P212121
Unit cell:
a: 74.149Å b: 80.32Å c: 118.13Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.194 0.192 0.229
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

7 review citations

Primary cilia biogenesis and associated retinal ciliopathies.
Chen et al. (2021)
6 more

1 mention without citation

The Ciliopathy-Associated Cep104 Protein Interacts with Tubulin and Nek1 Kinase.
Al-Jassar et al. (2017)