› 5lyp

X-ray diffraction
1.55Å resolution

Crystal structure of the Tpr Domain of Sgt2.

Released:
DOI: 10.2210/pdb5lyp/pdb
PDB entry 5lyp coloured by chain, front view.
PDB entry 5lyp coloured by chain, side view.
PDB entry 5lyp coloured by chain, top view.
Source organism: Saccharomyces cerevisiae
Primary publication:
Structure and Interactions of the TPR Domain of Sgt2 with Yeast Chaperones and Ybr137wp.
Krysztofinska EM, Evans NJ, Thapaliya A, Murray JW, Morgan RML, Martinez-Lumbreras S, Isaacson RL
Front Mol Biosci 4 68 (2017)
PMID: 29075633

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-171296 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Small glutamine-rich tetratricopeptide repeat-containing protein 2 Chain: A
Molecule details ›
Chain: A
Length: 140 amino acids
Theoretical weight: 15.64 KDa
Source organism: Saccharomyces cerevisiae
Expression system: Escherichia coli
UniProt:
  • Canonical: Q12118 (Residues: 93-229; Coverage: 40%)
Gene names: SGT2, UNF346, YOR007C
Sequence domains: Tetratricopeptide repeat
Structure domains: Tetratricopeptide repeat domain

Ligands and Environments

1 bound ligand:
Ligand BO4 1 x BO4
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I04
Spacegroup: P212121
Unit cell:
a: 36.861Å b: 50.76Å c: 67.116Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.195 0.194 0.218
Expression system: Escherichia coli

Quick links

Citations

6 review citations

The Ways of Tails: the GET Pathway and more.
Borgese et al. (2019)
5 more

2 mentions without citation

Structure and Interactions of the TPR Domain of Sgt2 with Yeast Chaperones and Ybr137wp.
Krysztofinska et al. (2017)
1 more