Function and Biology Details
Reactions catalysed:
Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1)
3'-end directed exonucleolytic cleavage of viral RNA-DNA hybrid
Endonucleolytic cleavage to 5'-phosphomonoester.
dUTP + H(2)O = dUMP + diphosphate
Biochemical function:
Biological process:
Cellular component:
- not assigned
Structure analysis Details
Assembly composition:
hetero 22-mer (preferred)
Assembly name:
Integrase and DNA (preferred)
PDBe Complex ID:
PDB-CPX-119001 (preferred)
Entry contents:
1 distinct polypeptide molecule
3 distinct DNA molecules
3 distinct DNA molecules
Macromolecules (4 distinct):
Integrase
Molecule details ›
Chains: A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P
Length: 281 amino acids
Theoretical weight: 32.37 KDa
Source organism: Visna/maedi virus EV1 KV1772
Expression system: Escherichia coli
UniProt:
Sequence domains:
Length: 281 amino acids
Theoretical weight: 32.37 KDa
Source organism: Visna/maedi virus EV1 KV1772
Expression system: Escherichia coli
UniProt:
- Canonical:
P35956 (Residues: 1226-1506; Coverage: 19%)
Sequence domains:
