› 5m1l

Solution NMR

Structure of DNA AGCGA-quadruplex adopted by 15-mer d(GCGAGGGAGCGAGGG), VK34, oligonucleotide found in regulatory region of the PLEKHG3 human gene

Released:
DOI: 10.2210/pdb5m1l/pdb
PDB entry 5m1l coloured by chain, ensemble of 10 models, front view.
PDB entry 5m1l coloured by chain, ensemble of 10 models, side view.
PDB entry 5m1l coloured by chain, ensemble of 10 models, top view.
Source organism: Homo sapiens
Primary publication:
Tetrahelical structural family adopted by AGCGA-rich regulatory DNA regions.
Kocman V, Plavec J
Nat Commun 8 15355 (2017)
PMID: 28513602

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-119002 (preferred)
Entry contents:
1 distinct DNA molecule
Macromolecule:
DNA (5'-D(*GP*CP*GP*AP*GP*GP*GP*AP*GP*CP*GP*AP*GP*GP*G)-3') Chains: A, B
Molecule details ›
Chains: A, B
Length: 15 nucleotides
Theoretical weight: 4.77 KDa
Source organism: Homo sapiens
Expression system: Not provided

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 22%
Expression system: Not provided

Quick links

Citations

22 citation in other articles

A methyl-TROSY approach for NMR studies of high-molecular-weight DNA with application to the nucleosome core particle.
Abramov et al. (2020)
21 more

2 mentions without citation

Non-G Base Tetrads.
Escaja et al. (2022)
1 more