Function and Biology Details
Reaction catalysed:
ATP + [biotin carboxyl-carrier protein]-biotin-N(6)-L-lysine + hydrogencarbonate- = ADP + phosphate + [biotin carboxyl-carrier protein]-carboxybiotin-N(6)-L-lysine
Biochemical function:
Biological process:
Cellular component:
Structure analysis Details
Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-161259 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Biotin-dependent acyl-coenzyme A carboxylase alpha3 subunit
Molecule details ›
Chains: A, B
Length: 614 amino acids
Theoretical weight: 65.46 KDa
Source organism: Mycobacterium tuberculosis H37Rv
Expression system: Escherichia coli
UniProt:
Sequence domains:
Length: 614 amino acids
Theoretical weight: 65.46 KDa
Source organism: Mycobacterium tuberculosis H37Rv
Expression system: Escherichia coli
UniProt:
- Canonical:
P96890 (Residues: 1-600; Coverage: 100%)
Sequence domains:
- Biotin carboxylase, N-terminal domain
- Carbamoyl-phosphate synthase L chain, ATP binding domain
- Biotin carboxylase C-terminal domain
- Biotin-requiring enzyme
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
X-ray source:
SLS BEAMLINE X06SA
Spacegroup:
P212121
Expression system: Escherichia coli
