› 5mvt

X-ray diffraction
1.9Å resolution

Crystal structure of an A-DNA dodecamer featuring an alternating pyrimidine-purine sequence

Released:
DOI: 10.2210/pdb5mvt/pdb
PDB entry 5mvt coloured by chain, front view.
PDB entry 5mvt coloured by chain, side view.
PDB entry 5mvt coloured by chain, top view.
Source organism: synthetic construct
Primary publication:
5-Formylcytosine does not change the global structure of DNA.
Hardwick JS, Ptchelkine D, El-Sagheer AH, Tear I, Singleton D, Phillips SEV, Lane AN, Brown T
Nat Struct Mol Biol 24 544-552 (2017)
PMID: 28504696

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-119041 (preferred)
Entry contents:
1 distinct DNA molecule
Macromolecule:
DNA Chains: A, B
Molecule details ›
Chains: A, B
Length: 12 nucleotides
Theoretical weight: 3.66 KDa
Source organism: synthetic construct
Expression system: Not provided

Ligands and Environments

1 bound ligand:
Ligand 3CO 1 x 3CO
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I04
Spacegroup: P3221
Unit cell:
a: 44.288Å b: 44.288Å c: 57.841Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.203 0.202 0.224
Expression system: Not provided

Quick links

Citations

7 review citations

Molecular methods for assessment of non-covalent metallodrug-DNA interactions.
Kellett et al. (2019)
6 more

4 mentions without citation

Chiral Systems Made from DNA.
Winogradoff et al. (2021)
3 more