› 5mx1

X-ray diffraction
2.17Å resolution

Crystal structure of human chondroadherin

Released:
DOI: 10.2210/pdb5mx1/pdb
PDB entry 5mx1 coloured by chain, front view.
PDB entry 5mx1 coloured by chain, side view.
PDB entry 5mx1 coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Structural and functional analysis of two small leucine-rich repeat proteoglycans, fibromodulin and chondroadherin.
Paracuellos P, Kalamajski S, Bonna A, Bihan D, Farndale RW, Hohenester E
Matrix Biol 63 106-116 (2017)
PMID: 28215822

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-127430 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Chondroadherin Chains: A, B
Molecule details ›
Chains: A, B
Length: 342 amino acids
Theoretical weight: 38.74 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
  • Canonical: O15335 (Residues: 20-359; Coverage: 100%)
Gene names: CHAD, SLRR4A
Sequence domains:
Structure domains: Ribonuclease Inhibitor

Ligands and Environments

3 bound ligands:
Ligand PO4 3 x PO4
Ligand NI 2 x NI
Ligand CL 1 x CL
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I24
Spacegroup: C2
Unit cell:
a: 215.45Å b: 60.7Å c: 57.66Å
α: 90° β: 100.6° γ: 90°
R-values:
R R work R free
0.191 0.188 0.24
Expression system: Homo sapiens

Quick links

Citations

6 review citations

Cartilage diseases.
Krishnan et al. (2018)
5 more

2 mentions without citation

From Translation to Protein Degradation as Mechanisms for Regulating Biological Functions: A Review on the SLRP Family in Skeletal Tissues.
Zappia et al. (2020)
1 more