› 5mxl

Solution NMR

Peptide-membrane interaction between targeting and lysis

Released:
DOI: 10.2210/pdb5mxl/pdb
PDB entry 5mxl coloured by chain, ensemble of 20 models, front view.
PDB entry 5mxl coloured by chain, ensemble of 20 models, side view.
PDB entry 5mxl coloured by chain, ensemble of 20 models, top view.
Source organism: synthetic construct
Primary publication:
Peptide-Membrane Interaction between Targeting and Lysis.
Stutz K, Müller AT, Hiss JA, Schneider P, Blatter M, Pfeiffer B, Posselt G, Kanfer G, Kornmann B, Wrede P, Altmann KH, Wessler S, Schneider G
ACS Chem Biol 12 2254-2259 (2017)
PMID: 28763193

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
  • not assigned
Sequence domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-166012 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
GLY-LEU-PHE-ASP-ILE-VAL-LYS-LYS-VAL-VAL-GLY-ALA-LEU-GLY-NH2 Chain: A
Molecule details ›
Chain: A
Length: 15 amino acids
Theoretical weight: 1.42 KDa
Source organism: synthetic construct
Expression system: synthetic construct

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 84%
Refinement method: simulated annealing
Expression system: synthetic construct

Quick links

Citations

1 review citation

Membrane Active Peptides and Their Biophysical Characterization.
Avci et al. (2018)
4 other articles

1 mention without citation

Morphing of Amphipathic Helices to Explore the Activity and Selectivity of Membranolytic Antimicrobial Peptides.
Müller et al. (2020)