› 5mzn

X-ray diffraction
1.79Å resolution

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-169411 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Helicase SEN1 Chain: A
Molecule details ›
Chain: A
Length: 749 amino acids
Theoretical weight: 85.17 KDa
Source organism: Saccharomyces cerevisiae S288C
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: Q00416 (Residues: 1095-1470, 1539-1904; Coverage: 33%)
Gene names: L9576.1, SEN1, YLR430W
Sequence domains:

Ligands and Environments

5 bound ligands:
Ligand ADP 1 x ADP
Ligand EDO 40 x EDO
Ligand GOL 12 x GOL
Ligand PEG 11 x PEG
Ligand MG 1 x MG
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SLS BEAMLINE X06DA
Spacegroup: P21212
Unit cell:
a: 90.285Å b: 171.944Å c: 69.094Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.153 0.153 0.184
Expression system: Escherichia coli BL21

Quick links

Citations

5 review citations

Untangling the crosstalk between BRCA1 and R-loops during DNA repair.
San Martin Alonso et al. (2021)
4 more

6 mentions without citation

The Nrd1-Nab3-Sen1 transcription termination complex from a structural perspective.
Chaves-Arquero et al. (2023)
5 more