› 5n4l

X-ray diffraction
3.2Å resolution

Rat ceruloplasmin trigonal form

Released:
DOI: 10.2210/pdb5n4l/pdb
PDB entry 5n4l coloured by chain, front view.
PDB entry 5n4l coloured by chain, side view.
PDB entry 5n4l coloured by chain, top view.
Source organism: Rattus norvegicus
Primary publication:
Rat ceruloplasmin: a new labile copper binding site and zinc/copper mosaic.
Samygina VR, Sokolov AV, Bourenkov G, Schneider TR, Anashkin VA, Kozlov SO, Kolmakov NN, Vasilyev VB
Metallomics 9 1828-1838 (2017)
PMID: 29177316

Function and Biology Details

Reaction catalysed: 
4 Fe(2+) + 4 H(+) + O(2) = 4 Fe(3+) + 2 H(2)O
Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-146681 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Ceruloplasmin Chains: A, B
Molecule details ›
Chains: A, B
Length: 1034 amino acids
Theoretical weight: 118 KDa
Source organism: Rattus norvegicus
UniProt:
  • Canonical: P13635 (Residues: 20-1053; Coverage: 99%)
Gene name: Cp
Sequence domains:
Structure domains: Cupredoxins - blue copper proteins

Ligands and Environments

3 bound ligands:
Ligand CU 11 x CU
Ligand CA 2 x CA
Ligand NA 2 x NA
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: PETRA III, EMBL c/o DESY BEAMLINE P14 (MX2)
Spacegroup: P3221
Unit cell:
a: 128.23Å b: 128.23Å c: 407.66Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.197 0.193 0.265

Quick links

Citations

3 review citations

Silver Ions as a Tool for Understanding Different Aspects of Copper Metabolism.
Puchkova et al. (2019)
2 more