Function and Biology Details
Reaction catalysed:
ATP + a protein = ADP + a phosphoprotein
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
- Mitogen-activated protein (MAP) kinase p38-like
- PPM-type phosphatase-like domain
- PPM-type phosphatase-like domain superfamily
- Mitogen-activated protein (MAP) kinase, conserved site
- Protein kinase, ATP binding site
- Protein kinase domain
- Protein kinase-like domain superfamily
- Mitogen-activated protein kinase 14
1 more domain
Structure analysis Details
Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-155654 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
TGF-beta-activated kinase 1 and MAP3K7-binding protein 1
Molecule details ›
Chains: A, B, C, D
Length: 504 amino acids
Theoretical weight: 54.7 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Sequence domains: Protein phosphatase 2C
Length: 504 amino acids
Theoretical weight: 54.7 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical:
Q15750 (Residues: 1-504; Coverage: 100%)
Sequence domains: Protein phosphatase 2C
Mitogen-activated protein kinase 14
Molecule details ›
Chains: E, F, G, H
Length: 360 amino acids
Theoretical weight: 41.5 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
Sequence domains: Protein kinase domain
Structure domains:
Length: 360 amino acids
Theoretical weight: 41.5 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
- Canonical: P47811 (Residues: 1-360; Coverage: 100%)
Sequence domains: Protein kinase domain
Structure domains:
