› 5o0r

X-ray diffraction
2.5Å resolution

Deglycosylated Nogo Receptor with native disulfide structure

Released:
DOI: 10.2210/pdb5o0r/pdb
PDB entry 5o0r coloured by chain, front view.
PDB entry 5o0r coloured by chain, side view.
PDB entry 5o0r coloured by chain, top view.
Source organism: Mus musculus
Primary publication:
Nogo Receptor crystal structures with a native disulfide pattern suggest a novel mode of self-interaction.
Pronker MF, Tas RP, Vlieg HC, Janssen BJC
Acta Crystallogr D Struct Biol 73 860-876 (2017)
PMID: 29095159

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-189379 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Reticulon-4 receptor Chains: A, B
Molecule details ›
Chains: A, B
Length: 334 amino acids
Theoretical weight: 37.11 KDa
Source organism: Mus musculus
Expression system: Homo sapiens
UniProt:
  • Canonical: Q99PI8 (Residues: 26-348; Coverage: 72%)
Gene names: Ngr1, Nogor, Rtn4r
Sequence domains: Leucine rich repeat
Structure domains: Ribonuclease Inhibitor

Ligands and Environments

3 bound ligands:
Ligand NAG 5 x NAG
Ligand GOL 2 x GOL
Ligand CL 3 x CL
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID23-1
Spacegroup: P212121
Unit cell:
a: 46.728Å b: 111.654Å c: 114.835Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.255 0.252 0.303
Expression system: Homo sapiens

Quick links

Citations

1 citations in other articles

The Murine Neuronal Receptor NgR1 Is Dispensable for Reovirus Pathogenesis.
Aravamudhan et al. (2022)