› 5o0u

X-ray diffraction
0.99Å resolution

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-160699 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Beta/omega-theraphotoxin-Tp2a Chain: A
Molecule details ›
Chain: A
Length: 30 amino acids
Theoretical weight: 3.84 KDa
Source organism: Thrixopelma pruriens
Expression system: Not provided
UniProt:
  • Canonical: P83476 (Residues: 1-30; Coverage: 100%)

Ligands and Environments

2 bound ligands:
Ligand CL 2 x CL
Ligand EDO 2 x EDO
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 5.0.2
Spacegroup: R32
Unit cell:
a: 37.669Å b: 37.669Å c: 103.944Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.127 0.126 0.14
Expression system: Not provided

Quick links

Citations

2 review citations

Bioactive Peptides and Proteins from Centipede Venoms.
Han et al. (2022)
1 more

3 mentions without citation

Structure-Function and Therapeutic Potential of Spider Venom-Derived Cysteine Knot Peptides Targeting Sodium Channels.
Cardoso et al. (2019)
2 more