› 5o5g

X-ray diffraction
3.03Å resolution

Robo1 Ig1 to 4 crystal form 1

Released:
DOI: 10.2210/pdb5o5g/pdb
PDB entry 5o5g coloured by chain, front view.
PDB entry 5o5g coloured by chain, side view.
PDB entry 5o5g coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Robo1 Forms a Compact Dimer-of-Dimers Assembly.
Aleksandrova N, Gutsche I, Kandiah E, Avilov SV, Petoukhov MV, Seiradake E, McCarthy AA
Structure 26 320-328.e4 (2018)
PMID: 29307485

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-195377 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Roundabout homolog 1 Chain: A
Molecule details ›
Chain: A
Length: 385 amino acids
Theoretical weight: 42.83 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
  • Canonical: Q9Y6N7 (Residues: 63-446; Coverage: 24%)
Gene names: DUTT1, ROBO1
Sequence domains:

Ligands and Environments

1 bound ligand:
Ligand NAG 1 x NAG
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID14-4
Spacegroup: C2221
Unit cell:
a: 44.156Å b: 99.711Å c: 238.673Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.201 0.198 0.258
Expression system: Homo sapiens

Quick links

Citations

5 review citations

The Role of the Slit/Robo Signaling Pathway.
Tong et al. (2019)
4 more

2 mentions without citation

Robo1 Forms a Compact Dimer-of-Dimers Assembly.
Aleksandrova et al. (2018)
1 more