› 5ocn

X-ray diffraction
2.7Å resolution

Crystal structure of the forkhead domain of human FOXN1

Released:
DOI: 10.2210/pdb5ocn/pdb
PDB entry 5ocn coloured by chain, front view.
PDB entry 5ocn coloured by chain, side view.
PDB entry 5ocn coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Newman JA, Aitkenhead H, Pinkas DM, von Delft F, Arrowsmith CH, Edwwards A, Bountra C, Gileadi O

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-127446 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Forkhead box protein N1 Chains: A, B, C, D, E, F, G, H
Molecule details ›
Chains: A, B, C, D, E, F, G, H
Length: 99 amino acids
Theoretical weight: 11.52 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: O15353 (Residues: 270-366; Coverage: 15%)
Gene names: FOXN1, RONU, WHN
Sequence domains: Forkhead domain
Structure domains: Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain

Ligands and Environments

1 bound ligand:
Ligand K 8 x K
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I03
Spacegroup: P212121
Unit cell:
a: 42.141Å b: 78.203Å c: 263.479Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.253 0.251 0.284
Expression system: Escherichia coli BL21(DE3)

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