Function and Biology Details
Reaction catalysed:
(1a) 1-C-(indol-3-yl)glycerol 3-phosphate = indole + D-glyceraldehyde 3-phosphate
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
- Tryptophan synthase, alpha chain
- Tryptophan synthase beta chain-like, PALP domain superfamily
- Tryptophan synthase beta chain/beta chain-like
- Tryptophan synthase, beta chain
- Tryptophan synthase, beta chain, conserved site
- Tryptophan synthase beta chain-like, PALP domain
- Tryptophan synthase, alpha chain, active site
- Ribulose-phosphate binding barrel
2 more domains
Structure analysis Details
Assembly composition:
hetero tetramer (preferred)
Assembly name:
Tryptophan synthase (preferred)
PDBe Complex ID:
PDB-CPX-161442 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Tryptophan synthase alpha chain
Molecule details ›
Chains: A, C, E, G, I, K, M, O, Q, S, U, W
Length: 290 amino acids
Theoretical weight: 29.92 KDa
Source organism: Mycobacterium tuberculosis H37Rv
Expression system: Escherichia coli BL21(DE3)
UniProt:
Sequence domains: Tryptophan synthase alpha chain
Structure domains: Aldolase class I
Length: 290 amino acids
Theoretical weight: 29.92 KDa
Source organism: Mycobacterium tuberculosis H37Rv
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical:
P9WFY1 (Residues: 1-270; Coverage: 100%)
Sequence domains: Tryptophan synthase alpha chain
Structure domains: Aldolase class I
Tryptophan synthase beta chain
Molecule details ›
Chains: B, D, F, H, J, L, N, P, R, T, V, X
Length: 442 amino acids
Theoretical weight: 46.87 KDa
Source organism: Mycobacterium tuberculosis H37Rv
Expression system: Escherichia coli BL21(DE3)
UniProt:
Sequence domains: Pyridoxal-phosphate dependent enzyme
Structure domains: Rossmann fold
Length: 442 amino acids
Theoretical weight: 46.87 KDa
Source organism: Mycobacterium tuberculosis H37Rv
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical: P9WFX9 (Residues: 1-421; Coverage: 100%)
Sequence domains: Pyridoxal-phosphate dependent enzyme
Structure domains: Rossmann fold
