5osb

X-ray diffraction
3.8Å resolution

GLIC-GABAAR alpha1 chimera crystallized in complex with THDOC at pH4.5

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
homo pentamer (preferred)
PDBe Complex ID:
PDB-CPX-158704 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Gamma-aminobutyric acid receptor subunit alpha-1; Proton-gated ion channel Chains: A, B, C, D, E
Molecule details ›
Chains: A, B, C, D, E
Length: 336 amino acids
Theoretical weight: 38.64 KDa
Source organisms: Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: Q7NDN8 (Residues: 44-236, 270-271; Coverage: 62%)
  • Canonical: P62812 (Residues: 250-284, 287-338, 417-455; Coverage: 29%)
Gene names: Gabra-1, Gabra1, glr4197, glvI
Sequence domains:
Structure domains:

Ligands and Environments

3 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID23-1
Spacegroup: C2
Unit cell:
a: 185.218Å b: 133.507Å c: 162.263Å
α: 90° β: 103.41° γ: 90°
R-values:
R R work R free
0.244 0.241 0.29
Expression system: Spodoptera frugiperda