5qpe

X-ray diffraction
1.77Å resolution

PanDDA analysis group deposition -- Crystal Structure of T. cruzi FPPS in complex with FMOPL000295a

Released:
Source organism: Trypanosoma cruzi
Entry authors: Petrick JK, Nelson ER, Muenzker L, Krojer T, Douangamath A, Brandao-Neto J, von Delft F, Dekker C, Jahnke W

Function and Biology Details

Structure analysis Details

Assembly composition:
homo dimer (preferred)
PDBe Complex ID:
PDB-CPX-186689 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Farnesyl diphosphate synthase Chain: A
Molecule details ›
Chain: A
Length: 364 amino acids
Theoretical weight: 41.36 KDa
Source organism: Trypanosoma cruzi
Expression system: Escherichia coli
UniProt:
  • Canonical: Q8WS26 (Residues: 64-425; Coverage: 85%)
Sequence domains: Polyprenyl synthetase

Ligands and Environments

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I04-1
Spacegroup: P6122
Unit cell:
a: 57.861Å b: 57.861Å c: 395.379Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.201 0.198 0.247
Expression system: Escherichia coli