› 5sc7

X-ray diffraction
1.2Å resolution

CD44 PanDDA analysis group deposition -- The hyaluronan-binding domain of CD44 in complex with POB0120

Released:
DOI: 10.2210/pdb5sc7/pdb
PDB entry 5sc7 coloured by chain, front view.
PDB entry 5sc7 coloured by chain, side view.
PDB entry 5sc7 coloured by chain, top view.
Source organism: Mus musculus
Entry authors: Bradshaw WJ, Katis VL, Bezerra GA, Koekemoer L, von Delft F, Bountra C, Brennan PE, Gileadi O

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-147332 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
CD44 antigen Chain: A
Molecule details ›
Chain: A
Length: 152 amino acids
Theoretical weight: 16.97 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
  • Canonical: P15379 (Residues: 23-172; Coverage: 20%)
Gene names: Cd44, Ly-24
Sequence domains: Extracellular link domain

Ligands and Environments

4 bound ligands:
Ligand W2M 1 x W2M
Ligand DMS 5 x DMS
Ligand EDO 2 x EDO
Ligand SO4 1 x SO4
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I04-1
Spacegroup: P21
Unit cell:
a: 31.209Å b: 82.106Å c: 32.401Å
α: 90° β: 118.26° γ: 90°
R-values:
R R work R free
0.159 0.157 0.182
Expression system: Escherichia coli

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