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› 5t9t

X-ray diffraction
3.5Å resolution

Protocadherin Gamma B2 extracellular cadherin domains 1-5

Released:
DOI: 10.2210/pdb5t9t/pdb
Model geometry
Fit model/data
PDB entry 5t9t coloured by chain, front view.
PDB entry 5t9t coloured by chain, side view.
PDB entry 5t9t coloured by chain, top view.
Source organism: Mus musculus
Primary publication:
γ-Protocadherin structural diversity and functional implications.
Goodman KM, Rubinstein R, Thu CA, Mannepalli S, Bahna F, Ahlsén G, Rittenhouse C, Maniatis T, Honig B, Shapiro L
OpenAccess logo Elife 5 (2016)
PMID: 27782885

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-185082 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecules (2 distinct):
Cadherin domain-containing protein Chains: A, B
Molecule details ›
Chains: A, B
Length: 535 amino acids
Theoretical weight: 59.42 KDa
Source organism: Mus musculus
Expression system: Homo sapiens
UniProt:
  • Canonical: Q8K486 (Residues: 30-556; Coverage: 57%)
Sequence domains:
Structure domains: Cadherins

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG, BMA, FUC
Carbohydrate polymer
3 bound ligands:
Ligand CA 26 x CA
Ligand MAN 11 x MAN
Ligand NAG 3 x NAG
No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this entry.
X-ray source: APS BEAMLINE 24-ID-E
Spacegroup: P21
Unit cell:
a: 80.722Å b: 118.067Å c: 98.19Å
α: 90° β: 103.91° γ: 90°
R-values:
R R work R free
0.215 0.213 0.256
Expression system: Homo sapiens

Quick links

Citations

12 review citations

Regulation of neural circuit formation by protocadherins.
Peek et al. (2017)
11 more

4 mentions without citation

Visualization of clustered protocadherin neuronal self-recognition complexes.
Brasch et al. (2019)
3 more