› 5tcq

Electron Microscopy
3.6Å resolution

Near-atomic resolution cryo-EM structure of the Salmonella SPI-1 type III secretion injectisome secretin InvG

Released:
DOI: 10.2210/pdb5tcq/pdb
PDB entry 5tcq coloured by chain, front view.
PDB entry 5tcq coloured by chain, side view.
PDB entry 5tcq coloured by chain, top view.
Source organism: Salmonella enterica subsp. enterica serovar Typhimurium
Primary publication:
Near-atomic-resolution cryo-EM analysis of the Salmonella T3S injectisome basal body.
Worrall LJ, Hong C, Vuckovic M, Deng W, Bergeron JRC, Majewski DD, Huang RK, Spreter T, Finlay BB, Yu Z, Strynadka NCJ
Nature 540 597-601 (2016)
PMID: 27974800
Related structures: EMD-8399

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo pentadecamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-152993 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
SPI-1 type 3 secretion system secretin Chains: A, B, C, D, E, F, G, H, I, J, K, L, M, N, O
Molecule details ›
Chains: A, B, C, D, E, F, G, H, I, J, K, L, M, N, O
Length: 562 amino acids
Theoretical weight: 61.84 KDa
Source organism: Salmonella enterica subsp. enterica serovar Typhimurium
UniProt:
  • Canonical: P35672 (Residues: 1-562; Coverage: 100%)
Gene names: STM2898, invG, sctC1
Sequence domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 3.6Å
Relevant EMDB volumes: EMD-8399

Quick links

Citations

20 review citations

Protein-Injection Machines in Bacteria.
Galán et al. (2018)
19 more

3 mentions without citation

Cryo-EM analysis of the T3S injectisome reveals the structure of the needle and open secretin.
Hu et al. (2018)
2 more