› 5te5

X-ray diffraction
4.01Å resolution

Crystal structure of Bos taurus opsin regenerated with 6-carbon ring retinal chromophore

Released:
DOI: 10.2210/pdb5te5/pdb
PDB entry 5te5 coloured by chain, front view.
PDB entry 5te5 coloured by chain, side view.
PDB entry 5te5 coloured by chain, top view.
Source organism: Bos taurus
Primary publication:
Photocyclic behavior of rhodopsin induced by an atypical isomerization mechanism.
Gulati S, Jastrzebska B, Banerjee S, Placeres ÁL, Miszta P, Gao S, Gunderson K, Tochtrop GP, Filipek S, Katayama K, Kiser PD, Mogi M, Stewart PL, Palczewski K
Proc Natl Acad Sci U S A 114 E2608-E2615 (2017)
PMID: 28289214

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-136065 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Rhodopsin Chain: A
Molecule details ›
Chain: A
Length: 349 amino acids
Theoretical weight: 39.06 KDa
Source organism: Bos taurus
UniProt:
  • Canonical: P02699 (Residues: 1-348; Coverage: 100%)
Gene name: RHO
Sequence domains:

Ligands and Environments

1 bound ligand:
Ligand 7AB 1 x 7AB
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 24-ID-C
Spacegroup: P3121
Unit cell:
a: 81.725Å b: 81.725Å c: 200.012Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.316 0.314 0.357

Quick links

Citations

5 review citations

Dynamic lipid turnover in photoreceptors and retinal pigment epithelium throughout life.
Lewandowski et al. (2022)
4 more

8 mentions without citation

Structural Basis for G Protein-Coupled Receptor Activation.
Manglik et al. (2017)
7 more