› 5tji

Electron Microscopy
3.8Å resolution

Ca2+ bound aplysia Slo1

Released:
DOI: 10.2210/pdb5tji/pdb
PDB entry 5tji coloured by chain, front view.
PDB entry 5tji coloured by chain, side view.
PDB entry 5tji coloured by chain, top view.
Source organism: Aplysia californica
Primary publication:
Structural basis for gating the high-conductance Ca2+-activated K+ channel.
Hite RK, Tao X, MacKinnon R
Nature 541 52-57 (2017)
PMID: 27974801
Related structures: EMD-8414

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-177761 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
BK channel Chain: A
Molecule details ›
Chain: A
Length: 1070 amino acids
Theoretical weight: 120.31 KDa
Source organism: Aplysia californica
Expression system: Trichoplusia ni
UniProt:
  • Canonical: Q5QJC5 (Residues: 1-1070; Coverage: 100%)
Sequence domains:

Ligands and Environments

1 bound ligand:
Ligand PGW 1 x PGW
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 3.8Å
Relevant EMDB volumes: EMD-8414
Expression system: Trichoplusia ni

Quick links

Citations

24 review citations

Intracellular Ca2+ Sensing: Its Role in Calcium Homeostasis and Signaling.
Bagur et al. (2017)
23 more

22 mentions without citation

Recent advances in our understanding of the structure and function of more unusual cation channels.
Brown et al. (2019)
21 more