› 5ty3

X-ray diffraction
1.25Å resolution

Crystal structure of K72A variant of Human Cytochrome c

Released:
DOI: 10.2210/pdb5ty3/pdb
PDB entry 5ty3 coloured by chain, front view.
PDB entry 5ty3 coloured by chain, side view.
PDB entry 5ty3 coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Effect of a K72A Mutation on the Structure, Stability, Dynamics, and Peroxidase Activity of Human Cytochrome c.
Nold SM, Lei H, Mou TC, Bowler BE
Biochemistry 56 3358-3368 (2017)
PMID: 28598148

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-161387 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Cytochrome c Chains: A, B
Molecule details ›
Chains: A, B
Length: 104 amino acids
Theoretical weight: 11.58 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: P99999 (Residues: 2-105; Coverage: 99%)
Gene names: CYC, CYCS
Sequence domains: Cytochrome c

Ligands and Environments

2 bound ligands:
Ligand HEC 2 x HEC
Ligand SO4 2 x SO4
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL9-2
Spacegroup: P21
Unit cell:
a: 56.794Å b: 37.902Å c: 60.254Å
α: 90° β: 116.79° γ: 90°
R-values:
R R work R free
0.148 0.147 0.166
Expression system: Escherichia coli BL21

Quick links

Citations

2 review citations

Wheel and Deal in the Mitochondrial Inner Membranes: The Tale of Cytochrome c and Cardiolipin.
Díaz-Quintana et al. (2020)
1 more

2 mentions without citation

Effect of a K72A Mutation on the Structure, Stability, Dynamics, and Peroxidase Activity of Human Cytochrome c.
Nold et al. (2017)
1 more